How to Create a Blue Rose

By Herb Wiggins, M.D.; Clinical Neurosciences; Discoverer/Creator of the Comparison Process/CP Theory/Model; 14 Mar. 2014
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There was recently a finalized attempt to make a blue rose and as usual came out with a purple one which was not honestly marketed, either. Plenty of those so called blue roses which are mostly purple, as well. But a true Blue Rose is not seen. & as the “Blue Rose” would make a LOT of money esp., and in the very least, at the Rose Bowl Parade every year, intense interest for 100’s of years has been made to find one.
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The problem is that the researchers are micromanaging and ignoring complex systems. Which is why the unintended purple rose came about, after years of work and $12 Millions invested, and failed. Simply by trying to put in a delphinidin gene into the rose genome, and then a modification, which didn’t work, either. The system is complex system, and cannot be reliably manipulated linearly, either. Everything has an effect on lots of other systems. So a single change is unlikely, like most linear thinking, to affect the whole and give the expected output.
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As usual, there was a disparity between what was expected and what was found. Festinger’s “cognitive dissonance” often seen with complex systems, struck again. OR as Asimov wrote about a leader in “The Foundation” series, “A direct man to the end!!!”
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This is how to do it and why it will work. There is a little known fact, yet it’s critical to understanding WHY and how things work between our ears. We know penicillin works. & we know did NOT at first know WHY 90 years ago, but THAT it did work to kill the bugs. We knew by its outcomes, by “its fruits”. IOW, our knowledge was incomplete, but we knew it worked, none the less. About 50 years later it was found out how it worked by blocking cell wall synthesis in susceptible bacteria. & with the appearance of PCN resistance, various new PCN’s have been created, including finding the cephalosporins, which were beta lactam rings, as well.
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But the antibiotic resistances occurred, again, unintended effects, unexpected. The universe of events doesn’t always work like our mental models do. There is a great difference between our models of events and how those actually work, as we are reminded nearly daily. The word is not the thing. The fallacy of the idealistic beliefs is that our brain outputs are NOT final truths, but stand only when those are compared to real events. The logical fallacy of idealisms is that brain outputs are somehow superior to events in existence. That’s what empiricism has taught us, and many don’t realize that fallacy even today, although Galileo knew it 400 years ago, very likely.
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This is how to block most all bacterial resistances; For the foreseeable future:
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Please peruse down to the paragraph beginning: ” Thus pharmacology is essentially massive trial and error….” That’s the beginning of the solution but takes one more, highly critical step to make it work without limits.
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We do NOT have to know how something works to know that it does. Paul B. Stark’s comparison methods show this occurring, as well.
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The Method of Comparison
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To get a deeper idea of what’s going on, let’s simply compare Luther Burbank’s methods of breeding plants he wanted, which was overwhelmingly successful compared to micromanaging and trying to insert genes into complex system genomes, which is highly unlikely to work, unless very, very lucky.
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What he did was to observe  & select the plants that he wanted in terms of taste, sizes and if they bred true or not. And then picked the ones he wanted by making a VERY great many of them, thus allowing genetic’s fullest diversity to present itself. In short, he let the natural systems do the genetics for him and didn’t have to delve into the genetics or manipulations of such complex systems such as 1000’s, even 10K’s of genes interacting, which cannot be solved logically nor mathematically, either. It’d take huge amounts of time. He Saw the larger picture, the forest for the trees.
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And that was basically how Burbank was so successful. He let natural systems show him the possibilities &  then chose the ones he wanted, and was wildly successful with this means. And why he succeeded whereas blue roses remain elusive.
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Thus we must use more complex system methods & let the natural systems do the sorting, looking NOT for the genetic manipulationa to work, but to let natural systems do the work of sorting for us.
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There are other blue pigments than delphinidine, for instance. Blue forget me nots have those, but expressing those in flowers is not easy. There is putunidin, also There are many kinds of flowers with blue pigments in them, but putting that gene into a rose plant, which has red pigments in the stems, and leaves, can be the problem. It will create a purple flower. So any kind of rose, which makes white flowers but does Not have the red pigments will work, possibly.
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The other point is making a blue flower plant cell fuse with a white flower rose. That’s the way to do it. Then choose those which have true blue rose outputs, that is, make a lot of plant fused cells, and then successively fuse with roses to make a blue rose, where the plant looks like a rose. That way, making sure at each stage, the flowers are blue. Let the natural systems select FOR a blue rose, against 100’s of trials. It will take some time but solves the sorting problem neatly, just as Burbank did.
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And that’s how to make a blue rose, very likely.

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